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Functional domains of Moloney murine leukemia virus integrase defined by mutation and complementation analysis.

Retroviral integrases perform two catalytic steps, 3' processing and strand transfer, that result in the stable insertion of the retroviral DNA into the host genome. Mutant M-MuLV integrases were constructed to define the functional domains important for 3' processing, strand transfer, and disintegr...

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Bibliografski detalji
Izdano u:J Virol
Glavni autori: Jonsson, C B, Donzella, G A, Gaucan, E, Smith, C M, Roth, M J
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1996
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190395/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8676485/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.7.4585-4597.1996
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