Functional domains of Moloney murine leukemia virus integrase defined by mutation and complementation analysis.

Retroviral integrases perform two catalytic steps, 3' processing and strand transfer, that result in the stable insertion of the retroviral DNA into the host genome. Mutant M-MuLV integrases were constructed to define the functional domains important for 3' processing, strand transfer, and...

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Библиографические подробности
Главные авторы: Jonsson, C B, Donzella, G A, Gaucan, E, Smith, C M, Roth, M J
Формат: Artigo
Язык:Inglês
Опубликовано: 1996
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC190395/
https://ncbi.nlm.nih.gov/pubmed/8676485
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