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Functional domains of Moloney murine leukemia virus integrase defined by mutation and complementation analysis.

Retroviral integrases perform two catalytic steps, 3' processing and strand transfer, that result in the stable insertion of the retroviral DNA into the host genome. Mutant M-MuLV integrases were constructed to define the functional domains important for 3' processing, strand transfer, and...

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Détails bibliographiques
Auteurs principaux: Jonsson, C B, Donzella, G A, Gaucan, E, Smith, C M, Roth, M J
Format: Artigo
Langue:Inglês
Publié: 1996
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC190395/
https://ncbi.nlm.nih.gov/pubmed/8676485
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