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Characterization of inhibition of M2 ion channel activity by BL-1743, an inhibitor of influenza A virus.

The influenza A virus M2 integral membrane protein has ion channel activity that can be inhibited by the antiviral drug amantadine. Recently, a spirene-containing compound, BL-1743 (2-[3-azaspiro (5,5)undecanol]-2-imidazoline), that inhibits influenza virus growth was identified (S. Kurtz, G. Lao, K...

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Detalhes bibliográficos
Main Authors: Tu, Q, Pinto, L H, Luo, G, Shaughnessy, M A, Mullaney, D, Kurtz, S, Krystal, M, Lamb, R A
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC190355/
https://ncbi.nlm.nih.gov/pubmed/8676445
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