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Activation of the M2 ion channel of influenza virus: a role for the transmembrane domain histidine residue.

To test the hypothesis that transmembrane domain histidine residue 37 of the M2 ion channel of influenza A virus mediates the low pH-induced activation of the channel, the residue was changed to glycine, glutamate, arginine, or lysine. The wild-type and altered M2 proteins were expressed in oocytes...

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Detalhes bibliográficos
Main Authors: Wang, C., Lamb, R. A., Pinto, L. H.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1236366/
https://ncbi.nlm.nih.gov/pubmed/8534806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0006-3495(95)80003-2
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