Influenza A Virus M(2) Ion Channel Activity Is Essential for Efficient Replication in Tissue Culture

The amantadine-sensitive ion channel activity of influenza A virus M(2) protein was discovered through understanding the two steps in the virus life cycle that are inhibited by the antiviral drug amantadine: virus uncoating in endosomes and M(2) protein-mediated equilibration of the intralumenal pH...

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Detalhes bibliográficos
Main Authors: Takeda, Makoto, Pekosz, Andrew, Shuck, Kevin, Pinto, Lawrence H., Lamb, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC135863/
https://ncbi.nlm.nih.gov/pubmed/11773413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.3.1391-1399.2002
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