Influenza A Virus M(2) Ion Channel Activity Is Essential for Efficient Replication in Tissue Culture

The amantadine-sensitive ion channel activity of influenza A virus M(2) protein was discovered through understanding the two steps in the virus life cycle that are inhibited by the antiviral drug amantadine: virus uncoating in endosomes and M(2) protein-mediated equilibration of the intralumenal pH...

Full description

Saved in:
Bibliographic Details
Main Authors: Takeda, Makoto, Pekosz, Andrew, Shuck, Kevin, Pinto, Lawrence H., Lamb, Robert A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Replication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC135863/
https://ncbi.nlm.nih.gov/pubmed/11773413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.3.1391-1399.2002
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items