A conserved domain of the Epstein-Barr virus nuclear antigens 3A and 3C binds to a discrete domain of Jkappa.
EBNA-3C can affect the LMP-1 promoter in both a positive and a negative manner through distinct DNA sequence elements. The viral transactivator EBNA-2 normally binds DNA indirectly via Jkappa to activate transcription, but this activation is prevented in the presence of EBNA-3C. The DNA element reco...
Збережено в:
| Опубліковано в:: | J Virol |
|---|---|
| Автори: | , , |
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
American Society for Microbiology (ASM)
1996
|
| Предмети: | |
| Онлайн доступ: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190353/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8676443/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.7.4228-4236.1996 |
| Теги: |
Немає тегів, Будьте першим, хто поставить тег для цього запису!
|