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Multi-Dimensional Time-Correlated Single Photon Counting (TCSPC) Fluorescence Lifetime Imaging Microscopy (FLIM) to Detect FRET in Cells

We present a novel, multi-dimensional, time-correlated single photon counting (TCSPC) technique to perform fluorescence lifetime imaging with a laser-scanning microscope operated at a pixel dwell-time in the microsecond range. The unsurpassed temporal accuracy of this approach combined with a high d...

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Detalhes bibliográficos
Main Authors: Duncan, R. R., Bergmann, A., Cousin, M. A., Apps, D. K., Shipston, M. J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1903372/
https://ncbi.nlm.nih.gov/pubmed/15230870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.0022-2720.2004.01343.x
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