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Including metabolite concentrations into flux balance analysis: thermodynamic realizability as a constraint on flux distributions in metabolic networks

BACKGROUND: In recent years, constrained optimization – usually referred to as flux balance analysis (FBA) – has become a widely applied method for the computation of stationary fluxes in large-scale metabolic networks. The striking advantage of FBA as compared to kinetic modeling is that it basical...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hoppe, Andreas, Hoffmann, Sabrina, Holzhütter, Hermann-Georg
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1903363/
https://ncbi.nlm.nih.gov/pubmed/17543097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-1-23
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