Positive interaction of nikkomycins and azoles against Candida albicans in vitro and in vivo.

Nikkomycins X and Z (NZ), competitive inhibitors of fungal chitin synthetase, were combined with azoles in a series of in vitro checkerboard assays to test for synergism against Candida spp. All combinations of nikkomycins and azoles tested resulted in marked synergistic activity against an isolate...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Hector, R F, Schaller, K
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1992
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190333/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1416829/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.6.1284
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