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Positive interaction of nikkomycins and azoles against Candida albicans in vitro and in vivo.

Nikkomycins X and Z (NZ), competitive inhibitors of fungal chitin synthetase, were combined with azoles in a series of in vitro checkerboard assays to test for synergism against Candida spp. All combinations of nikkomycins and azoles tested resulted in marked synergistic activity against an isolate...

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Bibliografische gegevens
Hoofdauteurs: Hector, R F, Schaller, K
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1992
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC190333/
https://ncbi.nlm.nih.gov/pubmed/1416829
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