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Positive interaction of nikkomycins and azoles against Candida albicans in vitro and in vivo.

Nikkomycins X and Z (NZ), competitive inhibitors of fungal chitin synthetase, were combined with azoles in a series of in vitro checkerboard assays to test for synergism against Candida spp. All combinations of nikkomycins and azoles tested resulted in marked synergistic activity against an isolate...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Hector, R F, Schaller, K
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190333/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1416829/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.6.1284
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