The envelope gp120 gene of human immunodeficiency virus type 1 determines the rate of CD4-positive T-cell depletion in SCID mice engrafted with human peripheral blood leukocytes.

We have used envelope recombinant viruses generated between two molecular clones of human immunodeficiency virus type 1 (HIV-1), T-cell-tropic HIV-1SF2 and macrophage-tropic HIV-1SF162, to assess pathogenic potential in the human peripheral blood leukocyte-reconstituted severe combined immune defici...

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書誌詳細
出版年:	J Virol
主要な著者:	Gulizia, R J, Levy, J A, Mosier, D E
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology (ASM) 1996
主題:	Research Article
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190315/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8648765/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.6.4184-4187.1996
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The envelope gp120 gene of human immunodeficiency virus type 1 determines the rate of CD4-positive T-cell depletion in SCID mice engrafted with human peripheral blood leukocytes.

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