Enhanced immunity to human immunodeficiency virus (HIV) envelope elicited by a combined vaccine regimen consisting of priming with a vaccinia recombinant expressing HIV envelope and boosting with gp160 protein.

Transmission studies have suggested that an optimal human immunodeficiency virus type 1 (HIV-1) vaccine should induce both neutralizing antibodies and cytolytic T cells to eliminate free virus and infected cells. A phase I trial in healthy HIV-1-seronegative persons was conducted with a combination...

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Main Authors: Cooney, E L, McElrath, M J, Corey, L, Hu, S L, Collier, A C, Arditti, D, Hoffman, M, Coombs, R W, Smith, G E, Greenberg, P D
Formato: Artigo
Idioma:Inglês
Publicado: 1993
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC45984/
https://ncbi.nlm.nih.gov/pubmed/8446603
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