A critical role for the TAR element in promoting efficient human immunodeficiency virus type 1 reverse transcription.

The regulation of human immunodeficiency virus type 1 (HIV-1) gene expression is dependent on the transactivator protein Tat and an RNA element extending from the transcription initiation site to +57 known as TAR. TAR forms a stable RNA secondary structure which is critical for high levels of HIV-1...

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Bibliographic Details
Main Authors: Harrich, D, Ulich, C, Gaynor, R B
Format: Artigo
Language:Inglês
Published: 1996
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC190280/
https://ncbi.nlm.nih.gov/pubmed/8648739
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