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Identification of a highly conserved sequence element at the 3' terminus of hepatitis C virus genome RNA.

Previous reports suggest that the hepatitis C virus (HCV) genome RNA terminates with homopolymer tracts of either poly(U) or poly(A). By ligation of synthetic oligonucleotides followed by reverse transcription-PCR, cDNA cloning, and sequence analysis, we determined the 3'-terminal sequence of H...

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Bibliographic Details
Main Authors: Kolykhalov, A A, Feinstone, S M, Rice, C M
Format: Artigo
Language:Inglês
Published: 1996
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC190207/
https://ncbi.nlm.nih.gov/pubmed/8648666
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