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Hybrid proteins between Pseudomonas aeruginosa exotoxin A and poliovirus 2Apro cleave p220 in HeLa cells.

Cleavage of p220, a component of the initiation factor eIF-4F, has been correlated with the inhibition of host translation during poliovirus infection. To obtain p220 cleavage in the absence of any other poliovirus gene products, hybrid proteins containing Pseudomonas aeruginosa exotoxin A and polio...

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Bibliographic Details
Main Authors: Novoa, I, Cotten, M, Carrasco, L
Format: Artigo
Language:Inglês
Published: 1996
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC190201/
https://ncbi.nlm.nih.gov/pubmed/8627818
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