In vivo model of adeno-associated virus vector persistence and rescue.

Gene therapy vectors based on human DNA viruses could be mobilized or rescued from individuals who are subsequently infected with the corresponding wild-type (wt) helper viruses. This phenomenon has been effectively modeled in vitro with both adenovirus (Ad) and adeno-associated virus (AAV) vectors...

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Autors principals: Afione, S A, Conrad, C K, Kearns, W G, Chunduru, S, Adams, R, Reynolds, T C, Guggino, W B, Cutting, G R, Carter, B J, Flotte, T R
Format: Artigo
Idioma:Inglês
Publicat: 1996
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC190187/
https://ncbi.nlm.nih.gov/pubmed/8627804
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