Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors.

The ability of recombinant adeno-associated virus (AAV) to transduce cells with a marker gene in vitro was found to be substantially increased by the presence of adenovirus. Transfection experiments with adenovirus genomic DNA suggest that this increase is not facilitated by adenovirus-mediated vira...

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Detalles Bibliográficos

Publicado en:	J Virol
Autores principales:	Ferrari, F K, Samulski, T, Shenk, T, Samulski, R J
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1996
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190186/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8627803/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.5.3227-3234.1996
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