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Systematic and intestinal antibody-secreting cell responses and correlates of protective immunity to human rotavirus in a gnotobiotic pig model of disease.

Neonatal gnotobiotic pigs orally inoculated with virulent (intestinal-suspension) Wa strain human rotavirus (which mimics human natural infection) developed diarrhea, and most pigs which recovered (87% protection rate) were immune to disease upon homologous virulent virus challenge at postinoculatio...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Yuan, L, Ward, L A, Rosen, B I, To, T L, Saif, L J
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1996
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190169/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8627786/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.5.3075-3083.1996
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