Antibody-Secreting Cell Responses and Protective Immunity Assessed in Gnotobiotic Pigs Inoculated Orally or Intramuscularly with Inactivated Human Rotavirus

Newborn gnotobiotic pigs were inoculated twice perorally (p.o.) (group 1) or intramuscularly (i.m.) (group 2) or three times i.m. (group 3) with inactivated Wa strain human rotavirus and challenged with virulent Wa human rotavirus 20 to 24 days later. To assess correlates of protection, antibody-sec...

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Main Authors: Yuan, Lijuan, Kang, S.-Y., Ward, Lucy A., To, Thanh L., Saif, Linda J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1998
Teme:
Viral Pathogenesis and Immunity
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC109380/
https://ncbi.nlm.nih.gov/pubmed/9420231
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