Human cytomegalovirus uracil DNA glycosylase is required for the normal temporal regulation of both DNA synthesis and viral replication.

Human cytomegalovirus (CMV) encodes a gene, UL114, whose product is homologous to the uracil DNA glycosylase and is highly conserved in all herpesviruses. This DNA repair enzyme excises uracil residues in DNA that result from the misincorporation of dUTP or spontaneous deamination of cytosine. We co...

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Detalles Bibliográficos

Publicado en:	J Virol
Principais autores:	Prichard, M N, Duke, G M, Mocarski, E S
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190161/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8627778/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.5.3018-3025.1996
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