Human cytomegalovirus uracil DNA glycosylase is required for the normal temporal regulation of both DNA synthesis and viral replication.

Human cytomegalovirus (CMV) encodes a gene, UL114, whose product is homologous to the uracil DNA glycosylase and is highly conserved in all herpesviruses. This DNA repair enzyme excises uracil residues in DNA that result from the misincorporation of dUTP or spontaneous deamination of cytosine. We co...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Prichard, M N, Duke, G M, Mocarski, E S
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1996
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190161/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8627778/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.5.3018-3025.1996
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