Cyclin-dependent kinases phosphorylate the adenovirus E1A protein, enhancing its ability to bind pRb and disrupt pRb-E2F complexes.

Lignende værker

• pRB-E2F1 Complexes Are Resistant to Adenovirus E1A-Mediated Disruption
  af: Seifried, L. A., et al.
  Udgivet: (2008)
• Phosphorylation of pRb by cyclin D kinase is necessary for development of cardiac hypertrophy
  af: Hinrichsen, R., et al.
  Udgivet: (2008)
• Hypo-phosphorylation of the retinoblastoma protein (pRb) by cyclin D:Cdk4/6 complexes results in active pRb
  af: Ezhevsky, Sergei A., et al.
  Udgivet: (1997)
• Cumulative Effect of Phosphorylation of pRB on Regulation of E2F Activity
  af: Brown, Vivette D., et al.
  Udgivet: (1999)
• Phosphorylation of pRB at Ser612 by Chk1/2 leads to a complex between pRB and E2F-1 after DNA damage
  af: Inoue, Yasumichi, et al.
  Udgivet: (2007)