Studies of neutralizing monoclonal antibody to human immunodeficiency virus type 1 reverse transcriptase: antagonistic and synergistic effects in reactions performed in the presence of nucleoside and nonnucleoside inhibitors, respectively.

We have assessed interactions between the reverse transcriptase (RT) of human immunodeficiency virus type 1 (HIV-1) and a neutralizing monoclonal antibody (1E8) that hinders binding of deoxynucleoside triphosphate (dNTP) substrates. Steady-state reactions with homopolymeric template-primers revealed...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Gu, Z, Li, X, Quan, Y, Parniak, M A, Wainberg, M A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1996
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190112/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8642696/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.4.2620-2626.1996
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