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In vivo sequence diversity of the protease of human immunodeficiency virus type 1: presence of protease inhibitor-resistant variants in untreated subjects.
We have evaluated the sequence diversity of the protease human immunodeficiency virus type 1 in vivo. Our analysis of 246 protease coding domain sequences obtained from 12 subjects indicates that amino acid substitutions predicted to give rise to protease inhibitor resistance may be present in patie...
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Autori principali: | , , , , , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
1996
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC190036/ https://ncbi.nlm.nih.gov/pubmed/8627733 |
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