Both Virus and Tumor Necrosis Factor Alpha Are Critical for Endothelium Damage in a Mouse Model of Dengue Virus-Induced Hemorrhage

Hemorrhage is a common clinical manifestation in dengue patients. However, the pathogenic mechanism of dengue virus (DV)-induced hemorrhage awaits clarification. We established a mouse model of DV hemorrhage using immunocompetent C57BL/6 mice by injecting DV serotype 2 strain 16681 intradermally. Wh...

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Bibliografiske detaljer
Main Authors: Chen, Hsuen-Chin, Hofman, Florence M., Kung, John T., Lin, Yang-Ding, Wu-Hsieh, Betty A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2007
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900309/
https://ncbi.nlm.nih.gov/pubmed/17360740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02575-06
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