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Enhancement by Tumor Necrosis Factor Alpha of Dengue Virus-Induced Endothelial Cell Production of Reactive Nitrogen and Oxygen Species Is Key to Hemorrhage Development

Hemorrhage is a severe manifestation of dengue disease. Virus strain and host immune response have been implicated as the risk factors for hemorrhage development. To delineate the complex interplay between the virus and the host, we established a dengue hemorrhage model in immune-competent mice. Mic...

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Main Authors: Yen, Yu-Ting, Chen, Hseun-Chin, Lin, Yang-Ding, Shieh, Chi-Chang, Wu-Hsieh, Betty A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593312/
https://ncbi.nlm.nih.gov/pubmed/18842737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00968-08
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