Conformation-Specific Antibodies Targeting the Trimer-of-Hairpins Motif of the Human T-Cell Leukemia Virus Type 1 Transmembrane Glycoprotein Recognize the Viral Envelope but Fail To Neutralize Viral Entry

Human T-cell leukemia virus type 1 (HTLV-1) entry into cells is dependent upon the viral envelope glycoprotein-catalyzed fusion of the viral and cellular membranes. Following receptor activation of the envelope, the transmembrane glycoprotein (TM) is thought to undergo a series of fusogenic conforma...

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Hlavní autoři: Mirsaliotis, Antonis, Nurkiyanova, Kulpash, Lamb, Daniel, Woof, Jenny M., Brighty, David W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2007
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900303/
https://ncbi.nlm.nih.gov/pubmed/17376912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02544-06
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