Small Interfering RNAs against the TAR RNA Binding Protein, TRBP, a Dicer Cofactor, Inhibit Human Immunodeficiency Virus Type 1 Long Terminal Repeat Expression and Viral Production

RNA interference (RNAi) is now widely used for gene silencing in mammalian cells. The mechanism uses the RNA-induced silencing complex, in which Dicer, Ago2, and the human immunodeficiency virus type 1 (HIV-1) TAR RNA binding protein (TRBP) are the main components. TRBP is a protein that increases H...

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Main Authors: Christensen, Helen S., Daher, Aïcha, Soye, Kaitlin J., Frankel, Lisa B., Alexander, Marina R., Lainé, Sébastien, Bannwarth, Sylvie, Ong, Chi L., Chung, Sean W. L., Campbell, Shahan M., Purcell, Damian F. J., Gatignol, Anne
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2007
Ábhair:
Genome Replication and Regulation of Viral Gene Expression
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900231/
https://ncbi.nlm.nih.gov/pubmed/17360756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01511-06
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