Identification of Determinants Involved in Initiation of Hepatitis C Virus RNA Synthesis by Using Intergenotypic Replicase Chimeras

The 5′ nontranslated region (NTR) and the X tail in the 3′ NTR are the least variable parts of the hepatitis C virus (HCV) genome and play an important role in the initiation of RNA synthesis. By using subgenomic replicons of the HCV isolates Con1 (genotype 1) and JFH1 (genotype 2), we characterized...

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Detalhes bibliográficos
Main Authors: Binder, Marco, Quinkert, Doris, Bochkarova, Olga, Klein, Rahel, Kezmic, Nikolina, Bartenschlager, Ralf, Lohmann, Volker
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900214/
https://ncbi.nlm.nih.gov/pubmed/17344294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00032-07
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