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Molecular Determinants of the Interaction between Coxsackievirus Protein 3A and Guanine Nucleotide Exchange Factor GBF1

The 3A protein of coxsackievirus B3 (CVB3), a small membrane protein that forms homodimers, inhibits endoplasmic reticulum-to-Golgi complex transport. Recently, we described the underlying mechanism by showing that the CVB3 3A protein binds to and inhibits the function of GBF1, a guanine nucleotide...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wessels, Els, Duijsings, Daniël, Lanke, Kjerstin H. W., Melchers, Willem J. G., Jackson, Catherine L., van Kuppeveld, Frank J. M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900206/
https://ncbi.nlm.nih.gov/pubmed/17329336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02680-06
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