Resistance to Chronic Wasting Disease in Transgenic Mice Expressing a Naturally Occurring Allelic Variant of Deer Prion Protein

Prion protein (PrP) is a required factor for susceptibility to transmissible spongiform encephalopathy or prion diseases. In transgenic mice, expression of prion protein (PrP) from another species often confers susceptibility to prion disease from that donor species. For example, expression of deer...

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Detalhes bibliográficos
Main Authors: Meade-White, Kimberly, Race, Brent, Trifilo, Matthew, Bossers, Alex, Favara, Cynthia, Lacasse, Rachel, Miller, Michael, Williams, Elizabeth, Oldstone, Michael, Race, Richard, Chesebro, Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900179/
https://ncbi.nlm.nih.gov/pubmed/17314157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02762-06
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