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A New Crucial Protein Interaction Element That Targets the Adenovirus E4-ORF1 Oncoprotein to Membrane Vesicles

Human adenovirus type 9 exclusively elicits mammary tumors in experimental animals, and the primary oncogenic determinant of this virus is the E4-ORF1 oncogene, as opposed to the well-known E1A and E1B oncogenes. The tumorigenic potential of E4-ORF1, as well as its ability to oncogenically stimulate...

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Autors principals: Chung, Sang-Hyuk, Frese, Kristopher K., Weiss, Robert S., Prasad, B. V. Venkataram, Javier, Ronald T.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900153/
https://ncbi.nlm.nih.gov/pubmed/17314165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02855-06
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