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Hijacking Dlg1 for Oncogenic Phosphatidylinositol 3-Kinase Activation in Human Epithelial Cells Is a Conserved Mechanism of Human Adenovirus E4-ORF1 Proteins

The E4-ORF1 gene of human adenoviruses encodes a 14-kDa protein that promotes viral replication as well as cellular metabolic reprogramming, survival, and transformation by constitutively activating cellular phosphatidylinositol 3-kinase (PI3K). We recently reported that the E4-ORF1 protein from sub...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Virol
मुख्य लेखकों: Kumar, Manish, Kong, Kathleen, Javier, Ronald T.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249130/
https://ncbi.nlm.nih.gov/pubmed/25253337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02324-14
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