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Role of the CD8(+) Dendritic Cell Subset in Transmission of Prions

Controversial results have been observed in mouse models regarding the role of lymphoid tissues in prion pathogenesis. To investigate the role of dendritic cells (DC), we used a transgenic mouse model. In this model (CD11c-N17Rac1), a significant reduction of CD8(+) CD11c(hi) DC has been described,...

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Autori principali: Sethi, Shneh, Kerksiek, Kristen M., Brocker, Thomas, Kretzschmar, Hans
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900152/
https://ncbi.nlm.nih.gov/pubmed/17301133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02345-06
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