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The DNA Binding Domain of a Papillomavirus E2 Protein Programs a Chimeric Nuclease To Cleave Integrated Human Papillomavirus DNA in HeLa Cervical Carcinoma Cells

Viral DNA binding proteins that direct nucleases or other protein domains to viral DNA in lytically or latently infected cells may provide a novel approach to modulate viral gene expression or replication. Cervical carcinogenesis is initiated by high-risk human papillomavirus (HPV) infection, and vi...

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Main Authors: Horner, Stacy M., DiMaio, Daniel
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology (ASM) 2007
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900111/
https://ncbi.nlm.nih.gov/pubmed/17392356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00232-07
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