Progression of Fibrosis during Chronic Hepatitis C Is Associated with Rapid Virus Evolution

Hepatic fibrosis is the primary mediator of disease due to chronic infection with hepatitis C virus (HCV). HCV exists as a quasispecies in each infected individual, and longitudinal viral sequence changes may reveal viral dynamics and the selection pressures applied by the host immune system. Thus,...

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Bibliografiska uppgifter
Huvudupphovsmän: Wang, Xiao-Hong, Netski, Dale M., Astemborski, Jacquie, Mehta, Shruti H., Torbenson, Michael S., Thomas, David L., Ray, Stuart C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2007
Ämnen:
Genetic Diversity and Evolution
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900109/
https://ncbi.nlm.nih.gov/pubmed/17329332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02276-06
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