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Progression of Biopsy-Measured Liver Fibrosis in Untreated Patients with Hepatitis C Infection: Non-Markov Multistate Model Analysis

BACKGROUND: Fibrosis stages from liver biopsies reflect liver damage from hepatitis C infection, but analysis is challenging due to their ordered but non-numeric nature, infrequent measurement, misclassification, and unknown infection times. METHODS: We used a non-Markov multistate model, accounting...

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Detalhes bibliográficos
Main Authors: Bacchetti, Peter, Boylan, Ross, Astemborski, Jacquie, Shen, Hui, Mehta, Shruti H., Thomas, David L., Terrault, Norah A., Monto, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103523/
https://ncbi.nlm.nih.gov/pubmed/21637766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020104
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