Characterization of mutants of influenza A virus selected with the neuraminidase inhibitor 4-guanidino-Neu5Ac2en.

The development of viral resistance to the neuraminidase (NA) inhibitor, 4-guanidino-Neu5Ac2en, of influenza viruses was studied by serial passage of A/Turkey/Minnesota/833/80 (H4N2) in Madin-Darby canine kidney cells in the presence of increasing concentrations of inhibitor. Resistant mutants selec...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Gubareva, L V, Bethell, R, Hart, G J, Murti, K G, Penn, C R, Webster, R G
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190009/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8627706/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.3.1818-1827.1996
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