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Induction of Apoptosis by the Severe Acute Respiratory Syndrome Coronavirus 7a Protein Is Dependent on Its Interaction with the Bcl-X(L) Protein
The severe acute respiratory syndrome coronavirus (SARS-CoV) 7a protein, which is not expressed by other known coronaviruses, can induce apoptosis in various cell lines. In this study, we show that the overexpression of Bcl-X(L), a prosurvival member of the Bcl-2 family, blocks 7a-induced apoptosis,...
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1900074/ https://ncbi.nlm.nih.gov/pubmed/17428862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00090-07 |
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