Ptf1a Binds to and Activates Area III, a Highly Conserved Region of the Pdx1 Promoter That Mediates Early Pancreas-Wide Pdx1 Expression

The critical pancreatic transcription factor Pdx1 is expressed throughout the pancreas early but enriched in insulin-producing β cells postnatally. Previous studies showed that the 5′ conserved promoter regions areas I and II (Pdx1(PB)) direct endocrine cell expression, while an adjacent region (Pdx...

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Detalhes bibliográficos
Main Authors: Wiebe, Peter O., Kormish, Jay D., Roper, Venus T., Fujitani, Yoshio, Alston, Ninche I., Zaret, Kenneth S., Wright, Christopher V. E., Stein, Roland W., Gannon, Maureen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900007/
https://ncbi.nlm.nih.gov/pubmed/17403901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01978-06
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