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Mbd2 Contributes to DNA Methylation-Directed Repression of the Xist Gene
Transcription of the Xist gene triggers X chromosome inactivation in cis and is therefore silenced on the X chromosome that remains active. DNA methylation contributes to this silencing, but the mechanism is unknown. As methylated DNA binding proteins (MBPs) are potential mediators of gene silencing...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1900000/ https://ncbi.nlm.nih.gov/pubmed/17353271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02204-06 |
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