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trans Autophosphorylation at DNA-Dependent Protein Kinase's Two Major Autophosphorylation Site Clusters Facilitates End Processing but Not End Joining

Recent studies have established that DNA-dependent protein kinase (DNA-PK) undergoes a series of autophosphorylation events that facilitate successful completion of nonhomologous DNA end joining. Autophosphorylation at sites in two distinct clusters regulates DNA end access to DNA end-processing fac...

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Detalhes bibliográficos
Main Authors: Meek, Katheryn, Douglas, Pauline, Cui, Xiaoping, Ding, Qi, Lees-Miller, Susan P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899996/
https://ncbi.nlm.nih.gov/pubmed/17353268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02366-06
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