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Negative Regulation of ASK1 by p21(Cip1) Involves a Small Domain That Includes Serine 98 That Is Phosphorylated by ASK1 In Vivo
The cyclin-dependent kinase inhibitor p21(Cip1) regulates multiple cellular functions and protects cells from genotoxic and other cellular stresses. Activation of apoptosis signal-regulating kinase 1 (ASK1) induced by inhibition of mTOR signaling leads to sustained phospho-c-Jun that is suppressed i...
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| Glavni autori: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2007
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1899956/ https://ncbi.nlm.nih.gov/pubmed/17325029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00086-06 |
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