A chimeric human immunodeficiency virus type 1 (HIV-1) minimal Rev response element-ribozyme molecule exhibits dual antiviral function and inhibits cell-cell transmission of HIV-1.

We have previously shown that hairpin ribozymes targeting the human immunodeficiency virus (HIV) genome can effectively inhibit virus replication in a variety of primary and cultured hematopoietic cells. To further increase antiviral potency and minimize the chance of viral resistance, we have now c...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Yamada, O, Kraus, G, Luznik, L, Yu, M, Wong-Staal, F
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1996
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189982/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8627679/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.3.1596-1601.1996
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