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Downstream regulatory elements increase acute and latent herpes simplex virus type 2 latency-associated transcript expression but do not influence recurrence phenotype or establishment of latency.

The role of putative promoter or activator sequences downstream of the herpes simplex virus type 2 latency-associated transcript (LAT) promoter and upstream of the LAT intron was investigated in vivo by constructing and evaluating mutant viruses with deletions in this region. The deletion of LAT pro...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Yoshikawa, T, Stanberry, L R, Bourne, N, Krause, P R
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189975/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8627672/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.3.1535-1541.1996
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