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Toxicity of tumor necrosis factor is synergistic with gamma-interferon and can be reduced with cyclooxygenase inhibitors.

In recent studies, we have demonstrated that recombinant human tumor necrosis factor (rH TNF), as a single agent, has only minimal therapeutic activity for the treatment of metastatic disease, but when combined with recombinant murine gamma-interferon (rM gamma-IFN), we observed significantly more t...

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Autori principali: Talmadge, J. E., Bowersox, O., Tribble, H., Lee, S. H., Shepard, H. M., Liggitt, D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1987
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899682/
https://ncbi.nlm.nih.gov/pubmed/3115109
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