Identification of a human immunodeficiency virus type 1 Tat epitope that is neuroexcitatory and neurotoxic.

Tat is an 86- to 104-amino-acid viral protein that activates human immunodeficiency virus type 1 expression, modifies several cellular functions, and causes neurotoxicity. Here, we determined the extent to which peptide fragments of human immunodeficiency virus type 1 BRU Tat1-86 produced neurotoxic...

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Vydáno v:	J Virol
Hlavní autoři:	Nath, A, Psooy, K, Martin, C, Knudsen, B, Magnuson, D S, Haughey, N, Geiger, J D
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1996
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189968/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8627665/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.3.1475-1480.1996
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