Attenuation stem-loop lesions in the 5' noncoding region of poliovirus RNA: neuronal cell-specific translation defects.

The nucleotide at position 480 in the 5' noncoding region of the viral RNA genome plays an important role in directing the attenuation phenotype of the Sabin vaccine strain of poliovirus type 1. In vitro translation studies have shown that the attenuated viral genomes of the Sabin strains direct lev...

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Detalles Bibliográficos

Publicado en:	J Virol
Autores principales:	Haller, A A, Stewart, S R, Semler, B L
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1996
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189967/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8627664/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.3.1467-1474.1996
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