Attenuation stem-loop lesions in the 5' noncoding region of poliovirus RNA: neuronal cell-specific translation defects.

The nucleotide at position 480 in the 5' noncoding region of the viral RNA genome plays an important role in directing the attenuation phenotype of the Sabin vaccine strain of poliovirus type 1. In vitro translation studies have shown that the attenuated viral genomes of the Sabin strains direct lev...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Haller, A A, Stewart, S R, Semler, B L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189967/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8627664/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.3.1467-1474.1996
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